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General Information

Document type
  • Journal Article
GE organism
  • Tobacco
GE trait
  • insect resistance
  • nematode resistance
Country
  • India

Results

Efficacy
  • positive effect

Host-generated double stranded RNA induces RNAi in plant-parasitic nematodes and protects the host from infection

Yadav, Bindhya Chal; Veluthambi, Karuppannan; Subramaniam, Kuppuswamy
Molecular & Biochemical Parasitology. 2006 August. 148(2):219-222

Link to full text (journal may charge for access)

PMID: 16678282 DOI: 10.1016/j.molbiopara.2006.03.013 ISSN: 0166-6851

Abstract

(Short correspondence) In many organisms, including the free-living nematode Caenorhabditis elegans, introduction of double stranded RNA (dsRNA) has been observed to deplete the endogenous mRNA that shares a high degree of sequence identity with the introduced dsRNA. Here we demonstrate that the dsRNA delivered through tobacco plants not only leads to almost total depletion of the target mRNA in the plant-parasitic nematode Meloidogyne incognita, but also provides the host effective resistance against the parasite.

Keywords

RNAi; Parasitic nematodes; Meloidogyne incognita; dsRNA

Funding

Funding source
  • Welllcome Trust
  • Council of Scientific and Industrial Research
Funding country
  • UK
  • India
Funding type
  • NGO: independent
  • government

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Cite this study

MLA

Yadav, Bindhya Chal, Karuppannan Veluthambi, Kuppuswamy Subramaniam. "Host-generated double stranded RNA induces RNAi in plant-parasitic nematodes and protects the host from infection." Molecular & Biochemical Parasitology 148.2 (2006): 219-222. Web. 13 Dec. 2018.

APA

Yadav, Bindhya Chal., Veluthambi, Karuppannan., & Subramaniam, Kuppuswamy. (2006). Host-generated double stranded RNA induces RNAi in plant-parasitic nematodes and protects the host from infection. Molecular & Biochemical Parasitology, 148(2), 219-222. doi:10.1016/j.molbiopara.2006.03.013

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