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General Information

Document type
  • Peer-reviewed journal article
GE organism
  • maize
GE trait
  • insect resistance
  • USA


Safety for consumption
  • no effect

A negative, double-blind, placebo-controlled challenge to genetically modified corn Open Access

Sutton, SA; Assa'ad, AH; Steinmetz, C; Rothenberg, ME
The Journal of Allergy and Clinical Immunology. 2003 November. 112(5):1011-1012

Link to full text (open access, freely available)

PMID: 14610498 DOI: 10.1016/S0091-6749(03)02024-4


[First paragraph in lieu of abstract] To the Editor: Starlink corn is a genetically engineered corn developed by Aventis CropScience (Research Triangle Park, NC) to express an insecticidal protein Cry9c (also known as Bt protein). This protein is derived from the bacterium Bacillus thuringensis and is directed at lepidopteran and coleopteran insects. Starlink corn also contains genes from Streptomyces hygroscopicus, which make the corn tolerant to glufosinate herbicides. In 1998, the US Environmental Protection Agency (EPA) approved registration of Starlink for restricted use as animal feed. In September 2000, the consumers’ group Friends of the Earth announced that traces of Starlink corn DNA were found in taco shells made by Kraft Foods (Phillip Morris, Northfield, Ill), signifying an inadvertent introduction of this transgenic food into the human food supply.1 This initiated the eventual recall of several hundred corn products by the US Food and Drug Administration (FDA), aswell as larger concerns about how this transgenic foodhad entered the human food supply.


Starlink; allergy; Bt; patient; placebo; negative; Cry9c; Keith Finger


Funding source
  • Division of Allergy and Immunology, Cincinati Children's Hospital Medical Center
Funding country
  • United States
Funding type
  • NGO: independent

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Cite this study


Sutton, SA, AH Assa'ad, C Steinmetz, ME Rothenberg. "A negative, double-blind, placebo-controlled challenge to genetically modified corn." The Journal of Allergy and Clinical Immunology 112.5 (2003): 1011-1012. Web. 17 Jul. 2024.


Sutton, SA., Assa'ad, AH., Steinmetz, C., & Rothenberg, ME. (2003). A negative, double-blind, placebo-controlled challenge to genetically modified corn. The Journal of Allergy and Clinical Immunology, 112(5), 1011-1012. doi:10.1016/S0091-6749(03)02024-4

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