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General Information

Document type
  • Peer-reviewed journal article
GE organism
  • maize
GE trait
  • insect resistance
  • Japan


Safety for consumption
  • no effect

Effects of feeding calves genetically modified corn bt11: a clinico-biochemical study Open Access

Shimada, N; Murata, H; Mikami, O; Yoshioka, M; Guruge, KS; Yamanaka, N; Nakajima, Y; Miyazaki, S
Journal of Veterinary Medical Science. 2006 October. 68(10):1113-1115

Link to full text (open access, freely available)

PMID: 17085894 DOI: 10.1292/jvms.68.1113


Genetically modified corn Bt11 is insect-resistant and expresses Cry1Ab toxin, an insecticidal protein, in kernels. Although Bt11 corn is considered safe based on animal performance, there are no reports available on the clinico-biochemical effects of feeding it to cattle. In this study, we evaluated the effects of feeding Bt11 to calves, using blood and ruminal clinico-biochemical parameters. Our three-month-long feeding experiment demonstrated that calves (n=6), fed with a ration containing 43.3% of Bt11 corn kernels as dry matter, did not develop any discernible clinical, hematological, biochemical, or ruminal abnormalities as compared with control calves (n=6) fed non-Bt11 corn. The results suggest that the transgenic Bt11 has no negative clinico-biochemical effects on calves.


Bt11, calf, clinico-biochemical parameters


Funding source
  • Ministry of Agriculture, Forestry, and Fisheries of Japan
Funding country
  • Japan
Funding type
  • government

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Cite this study


Shimada, N, H Murata, O Mikami, M Yoshioka, KS Guruge, N Yamanaka, Y Nakajima, S Miyazaki. "Effects of feeding calves genetically modified corn bt11: a clinico-biochemical study." Journal of Veterinary Medical Science 68.10 (2006): 1113-1115. Web. 24 Apr. 2024.


Shimada, N., Murata, H., Mikami, O., Yoshioka, M., Guruge, KS., Yamanaka, N., Nakajima, Y., & Miyazaki, S. (2006). Effects of feeding calves genetically modified corn bt11: a clinico-biochemical study. Journal of Veterinary Medical Science, 68(10), 1113-1115. doi:10.1292/jvms.68.1113

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