There are currently 402 studies in the GENERA database.

Advanced Search

General Information

Document type
  • Peer-reviewed journal article
GE organism
  • tobacco
  • cucumber
  • melon
  • tomato
  • squash
  • pepper
  • potato
GE trait
  • disease resistance
  • Italy


  • positive effect

Twenty years of transgenic plants resistant to Cucumber mosaic virus Review Article Open Access

Morroni, M; Thompson, JR; Tepfer, M
Molecular Plant-Microbe Interactions. 2008 June. 21(6):675-684

Link to full text (open access, freely available)

PMID: 18624632 DOI: 10.1094/MPMI-21-6-0675 ISSN: 0894-0282


Plant genetic engineering has promised researchers improved speed and flexibility with regard to the introduction of new traits into cultivated crops. A variety of approaches have been applied to produce virus-resistant transgenic plants, some of which have proven to be remarkably successful. Studies on transgenic resistance to Cucumber mosaic virus probably have been the most intense of any plant virus. Several effective strategies based on pathogen-derived resistance have been identified; namely, resistance mediated by the viral coat protein, the viral replicase, and post-transcriptional gene silencing. Techniques using non-pathogen-derived resistance strategies, some of which could offer broader resistance, generally have proven to be much less effective. Not only do the results obtained so far provide a useful guide to help focus on future strategies, but they also suggest that there are a number of possible mechanisms involved in conferring these resistances. Further detailed studies on the interplay between viral transgene-derived molecules and their host are needed in order to elucidate the mechanisms of resistance and pathogenicity.


CMV; cucumber mosaic virus; resistance; pathogenicity


Funding source
  • Fondazione Cassamarca (Cassamarca Foundation)
Funding country
  • Italy
Funding type
  • NGO: independent

Links to outside analysis of this resource

Please contact us if you know of an independent summary or analysis of this resource.

Cite this study


Morroni, M, JR Thompson, M Tepfer. "Twenty years of transgenic plants resistant to Cucumber mosaic virus." Molecular Plant-Microbe Interactions 21.6 (2008): 675-684. Web. 28 May. 2024.


Morroni, M., Thompson, JR., & Tepfer, M. (2008). Twenty years of transgenic plants resistant to Cucumber mosaic virus. Molecular Plant-Microbe Interactions, 21(6), 675-684. doi:10.1094/MPMI-21-6-0675

Please verify citations before use, citations are automatically generated based on information stored within the GENERA database and therefore may or may not be correct.