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General Information

Document type
  • Journal article
GE organism
  • rice
GE trait
  • quality
Country
  • Japan

Results

Safety for consumption
  • no effect

Safety assessment of rice genetically modified with soybean glycinin by feeding studies on rats Open Access

Momma, K; Hashimoto, W; Yoon, HJ; Ozawa, S; Fukuda, Y; Kawai, S; Takaiwa, F; Utsumi, S; Murata, K
Bioscience, Biotechnology, and Biochemistry . 2000 September. 64(9):1881-6

Link to full text (open access, freely available)

PMID: 11055391 DOI: 10.1271/bbb.64.1881 ISSN: 0916-8451

Abstract

Feeding studies on rice genetically modified with soybean glycinin were performed on rats for four weeks. The rats were divided into three groups, each being fed on (I) only a commercial diet, (II) this diet plus control rice and (III) this diet plus rice genetically modified with glycinin. The rats were fed with 10 g/kg-weight of rice every day by oral administration. During the test period, the rats in every group grew well without marked differences in appearance, food intake, body weight, or cumulative body weight gain. There were also no significant differences in the blood count, blood composition or internal organ weights among the rats. Necropsy at the end of the experiment indicated neither pathological symptoms nor histopathological abnormalities in the liver and kidney. Judging from these results, the rice genetically modified with glycinin is considered to have been essentially the same in nutritional and biochemical characteristics as the control rice.

Keywords

animal feeding study, food safety, genetically modified rice, soybean glycinin

Funding

Funding source
  • Bio-oriented Technology Research Advancement Institution of Japan (BRAIN)
Funding country
  • Japan
Funding type
  • government

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Cite this study

MLA

Momma, K, W Hashimoto, HJ Yoon, S Ozawa, Y Fukuda, S Kawai, F Takaiwa, S Utsumi, K Murata. "Safety assessment of rice genetically modified with soybean glycinin by feeding studies on rats ." Bioscience, Biotechnology, and Biochemistry 64.9 (2000): 1881-6 . Web. 26 Dec. 2024.

APA

Momma, K., Hashimoto, W., Yoon, HJ., Ozawa, S., Fukuda, Y., Kawai, S., Takaiwa, F., Utsumi, S., & Murata, K. (2000). Safety assessment of rice genetically modified with soybean glycinin by feeding studies on rats . Bioscience, Biotechnology, and Biochemistry , 64(9), 1881-6 . doi:10.1271/bbb.64.1881

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