The legislative mandates and proposed scope of the U.S. Environmental Protection Agency's (EPA) regulation of pesticides produced in plants are described. The first three Experimental Use Permits (EUPs) granted by EPA for field testing of plant-pesticides were for delta endotoxins from Bacillus thuringiensis expressed in cotton (Gossypium hirsutum L.), potato (Solanum tuberosum L.) and maize (Zea mays L.). In each instance, an environmental-fate assessment by the Agency found no significant risk of gene expression beyond the spatial and temporal limits of the proposed field tests.
LaSota, LR. "Evaluation by the United States Environmental Protection Agency of pesticidal substances produced in plants." Field Crops Research 45.3-Jan (1996): 181–186. Web. 21 Jul. 2019.
LaSota, LR. (1996). Evaluation by the United States Environmental Protection Agency of pesticidal substances produced in plants. Field Crops Research, 45(3-Jan), 181–186. doi:10.1016/0378-4290(95)00070-4
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