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General Information

Document type
  • Peer-reviewed journal article
Study Type
  • feeding study
  • horizontal gene transfer
GE organism
  • cucumber
GE trait
  • quality
  • marker
Country
  • Poland

Results

Safety for consumption
  • no effect

Evaluation of the possibility of horizontal gene transfer and accumulation of transgenic DNA from the diet in the bodies of rats. Open Access

Kosieradzka, I; Vasko, V; Szwacka, M; Przybysz, A; Fiedorowicz, Sz
Journal of Animal and Feed Sciences. 2010 19(307-315

Link to full text (open access, freely available)



Abstract

The procedures for GMO safety tests include traceability of transgenic protein and transgenic DNA if the plant constitutes a component in the diet for an animal. This is due to the possibility of horizontal transfer of genes, accumulation of transgenic DNA in consumer’s organs, or induction of antibiotic resistance in gastrointestinal tract microflora. The last possibility is related to the use of marker genes in the process of transformation. In an in vivo experiment conducted on laboratory rats with the use of transgenic cucumbers expressing the pre-prothaumatin gene, the presence of transgenic DNA in the tissue of kidneys and liver was not detected. Resistance to neomycin of gastrointestinal tract microflora of the rats fed the GMO diet was not found, despite the use of marker genes (npt II) in the process of transformation of the investigated plants.

Keywords

GM cucumber; gene transfer; antibiotic resistance; in vivo experiment; rats

Funding

Funding source
  • Warsaw Agricultural University
Funding country
  • Poland
Funding type
  • government

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Cite this study

MLA

Kosieradzka, I, V Vasko, M Szwacka, A Przybysz, Sz Fiedorowicz. "Evaluation of the possibility of horizontal gene transfer and accumulation of transgenic DNA from the diet in the bodies of rats.." Journal of Animal and Feed Sciences 19. (2010): 307-315. Web. 13 Dec. 2018.

APA

Kosieradzka, I., Vasko, V., Szwacka, M., Przybysz, A., & Fiedorowicz, Sz. (2010). Evaluation of the possibility of horizontal gene transfer and accumulation of transgenic DNA from the diet in the bodies of rats.. Journal of Animal and Feed Sciences, 19( ), 307-315.

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