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General Information

Document type
  • Peer-reviewed journal article
Study Type
  • review
  • history
GE organism
  • maize
GE trait
  • herbicide tolerance
Country
  • Switzerland, UK, France, Belgium, Germany

Results

Equivalence
  • no effect

History of safe use as applied to the safety assessment of novel foods and foods derived from genetically modified organisms Review Article

Constable, A; Jonas, D; Cockburn, A; Davi, A; Edwards, G; Hepburn, P; Herouet-Guicheney, C; Knowles, M; Moseley, B; Oberdörfer, R; Samuels, F
Food and Chemical Toxicology. 2007 December. 45(12):2513–2525

Link to full text (journal may charge for access)

PMID: 17692450 DOI: 10.1016/j.fct.2007.05.028 ISSN: 0278-6915

Abstract

Very few traditional foods that are consumed have been subjected to systematic toxicological and nutritional assessment, yet because of their long history and customary preparation and use and absence of evidence of harm, they are generally regarded as safe to eat. This 'history of safe use' of traditional foods forms the benchmark for the comparative safety assessment of novel foods, and of foods derived from genetically modified organisms. However, the concept is hard to define, since it relates to an existing body of information which describes the safety profile of a food, rather than a precise checklist of criteria. The term should be regarded as a working concept used to assist the safety assessment of a food product. Important factors in establishing a history of safe use include: the period over which the traditional food has been consumed; the way in which it has been prepared and used and at what intake levels; its composition and the results of animal studies and observations from human exposure. This paper is aimed to assist food safety professionals in the safety evaluation and regulation of novel foods and foods derived from genetically modified organisms, by describing the practical application and use of the concept of 'history of safe use'.

Keywords

Safety assessment; Novel foods; Genetically modified foods; History of safe use

Funding

Funding source
  • International Life Sciences Institute Europe
Funding country
  • Belgium
Funding type
  • NGO: same industry aligned

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Cite this study

MLA

Constable, A, D Jonas, A Cockburn, A Davi, G Edwards, P Hepburn, C Herouet-Guicheney, M Knowles, B Moseley, R Oberdörfer, F Samuels. "History of safe use as applied to the safety assessment of novel foods and foods derived from genetically modified organisms." Food and Chemical Toxicology 45.12 (2007): 2513–2525. Web. 21 Nov. 2018.

APA

Constable, A., Jonas, D., Cockburn, A., Davi, A., Edwards, G., Hepburn, P., Herouet-Guicheney, C., Knowles, M., Moseley, B., Oberdörfer, R., & Samuels, F. (2007). History of safe use as applied to the safety assessment of novel foods and foods derived from genetically modified organisms. Food and Chemical Toxicology, 45(12), 2513–2525. doi:10.1016/j.fct.2007.05.028

Please verify citations before use, citations are automatically generated based on information stored within the GENERA database and therefore may or may not be correct.