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General Information

Document type
  • Journal Article
GE organism
  • Multiple
GE trait
  • pharmaceutical
Country
  • Finland

Results

Efficacy
  • mixed

Transgenic crops for improved pharmaceutical products Review Article

Oksman-Caldentey, Kirsi-Marja; Hiltunen, Raimo
Field Crops Research. 1996 May. 45(3-Jan):57-69

Link to full text (journal may charge for access)

DOI: 10.1016/0378-4290(95)00059-3 ISSN: 0378-4290

Abstract

Transgenic plants have been obtained from a number of plant species, but only from a few medicinal plants. There are even fewer examples of studies on secondary metabolite production in transgenic medicinal plants. Because analyses have been performed on only a few plants far-reaching generalizations cannot be made. The secondary metabolite pathways are complicated, requiring several enzymatic steps to the desired end products used as pharmaceuticals. Thus, it is very difficult to regulate the production of secondary metabolites at the gene level. However, transgenic organ cultures, e.g. hairy roots and shooty teratomas with enhanced production capacity, have been obtained from several plant species via Agrobacterium transformation. In this review the possibilities and problems of producing pharmaceuticals by plant biotechnology are discussed. Comparison is made between whole plants and cell cultures, as well as conventional versus transgenic plants and in vitro cultures.

Keywords

pharmaceutical; Medicinal plants; Organ culture; Review; Secondary metabolites; Transgenic plants

Funding

Funding source
  • University of Helsinki, Finland
  • Academy of Finland
Funding country
  • Finland
Funding type
  • government

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Cite this study

MLA

Oksman-Caldentey, Kirsi-Marja, Raimo Hiltunen. "Transgenic crops for improved pharmaceutical products." Field Crops Research 45.3-Jan (1996): 57-69. Web. 25 Jul. 2017.

APA

Oksman-Caldentey, Kirsi-Marja., & Hiltunen, Raimo. (1996). Transgenic crops for improved pharmaceutical products. Field Crops Research, 45(3-Jan), 57-69. doi:10.1016/0378-4290(95)00059-3

Please verify citations before use, citations are automatically generated based on information stored within the GENERA database and therefore may or may not be correct.