There are currently 402 studies in the GENERA database.

Advanced Search

General Information

Document type
  • Peer-reviewed journal article
GE organism
  • kale
GE trait
  • insect resistance
Country
  • Taiwan

Results

Equivalence
  • no effect
Safety for consumption
  • mixed

Safety assessment and detection method of genetically modified Chinese Kale (Brassica oleracea cv. alboglabra )

Lin, CH; Lu, CT; Lin, HT; Pan, TM
Journal of Agricultural and Food Chemistry. 2009 February. 57(5):1876–1881

Link to full text (journal may charge for access)

PMID: 19216530 DOI: 10.1021/jf8034644

Abstract

Sporamins are tuberous storage proteins and account for 80% of soluble protein in sweet potato tubers with trypsin-inhibitory activity. The expression of sporamin protein in transgenic Chinese kale (line BoA 3-1) conferred insecticidal activity toward corn earworm [ Helicoverpa armigera (Hubner)] in a previous report. In this study, we present a preliminary safety assessment of transgenic Chinese kale BoA 3-1. Bioinformatic and simulated gastric fluid (SGF) analyses were performed to evaluate the allergenicity of sporamin protein. The substantial equivalence between transgenic Chinese kale and its wild-type host has been demonstrated by the comparison of important constituents. A reliable real-time polymerase chain reaction (PCR) detection method was also developed to control sample quality. Despite the results of most evaluations in this study being negative, the safety of sporamin in transgenic Chinese kale BoA 3-1 was uncluded because of the allergenic risk revealed by bioinformatic analysis.

Keywords

Sporamin; safety assessment; real-time PCR; allergenicity

Funding

Funding source
  • Department of Health of Taiwan
Funding country
  • China
Funding type
  • government

Links to outside analysis of this resource

Please contact us if you know of an independent summary or analysis of this resource.

Cite this study

MLA

Lin, CH, CT Lu, HT Lin, TM Pan. "Safety assessment and detection method of genetically modified Chinese Kale (Brassica oleracea cv. alboglabra )." Journal of Agricultural and Food Chemistry 57.5 (2009): 1876–1881. Web. 25 Sep. 2017.

APA

Lin, CH., Lu, CT., Lin, HT., & Pan, TM. (2009). Safety assessment and detection method of genetically modified Chinese Kale (Brassica oleracea cv. alboglabra ). Journal of Agricultural and Food Chemistry, 57(5), 1876–1881. doi:10.1021/jf8034644

Please verify citations before use, citations are automatically generated based on information stored within the GENERA database and therefore may or may not be correct.