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General Information

Document type
  • Peer-reviewed journal article
GE organism
  • chinese cabbage
GE trait
  • herbicide tolerance
Country
  • Korea

Results

Equivalence
  • no effect

Metabolic fingerprinting study on the substantial equivalence of genetically modified (GM) chinese cabbage to non-GM cabbage

Kim, JK; Ryu, TH; Kim, JH; Chu, SM; Yu, CY; Baek, HJ
Journal of the Korean Society for Applied Biological Chemistry. 2009 April. 52(2):186-192

Link to full text (journal may charge for access)

DOI: 10.3839/jksabc.2009.034 ISSN: 2234-344X

Abstract

Genetically modified (GM) Chinese cabbage containing the bar gene was compared to 24 non-GM Chinese cabbage varieties to evaluate unwanted changes in GM crops using HPLC-DAD-based metabolic fingerprinting to characterize polar metabolites containing flavonoids. No new compounds distinguishing GM crops from non-GM crops were observed using this technique. The GM crops had the similar flavonoid value as its nontransgenic counterpart (cv. Samjin). Moreover, the luteolin, quercetin, and kaempferol contents in GM Chinese cabbage were within the range of the 24 cultivars. The metabolome database included major 26 chemical species, which were analyzed with principal component analysis. The results clearly demonstrated that the time of sampling affects the metabolome. Moreover, the metabolic fingerprints showed a range of natural variability in the GM Chinese cabbage that was similar to that of the control at all times of sampling. Metabolic fingerprinting could potentially provide an innovative method for safety assessments of genetically modified organisms.

Keywords

Chinese cabbage; flavonoid; genetically modified crop; HPLC-DAD; metabolic fingerprinting; substantial equivalence

Funding

Funding source
  • National Academy of Agricultural Science. Rural Development Administration
Funding country
  • Korea
Funding type
  • government

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Cite this study

MLA

Kim, JK, TH Ryu, JH Kim, SM Chu, CY Yu, HJ Baek. "Metabolic fingerprinting study on the substantial equivalence of genetically modified (GM) chinese cabbage to non-GM cabbage." Journal of the Korean Society for Applied Biological Chemistry 52.2 (2009): 186-192. Web. 25 Sep. 2017.

APA

Kim, JK., Ryu, TH., Kim, JH., Chu, SM., Yu, CY., & Baek, HJ. (2009). Metabolic fingerprinting study on the substantial equivalence of genetically modified (GM) chinese cabbage to non-GM cabbage. Journal of the Korean Society for Applied Biological Chemistry, 52(2), 186-192. doi:10.3839/jksabc.2009.034

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