There are currently 402 studies in the GENERA database.

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General Information

Document type
  • Peer-reviewed journal article
GE organism
  • maize
GE trait
  • insect resistance
Country
  • Japan

Results

Safety for consumption
  • no effect

Longterm Biosafety Assessment of A Genetically Modified (GM) Plant: The Genetically Modified (GM) Insect-Resistant Bt11 Corn Does Not Affect the Performance of Multi-Generations or Life Span of Mice Open Access

Haryu, Y; Taguchi, Y; Itakura, E; Mikami, O; Miura, K; Saeki, T; Nakajima, Y
The Open Plant Science Journal . 2009 3(49-53

Link to full text (open access, freely available)

DOI: 10.2174/1874294700903010049 ISSN: 1874-2947

Abstract

The longterm performance of multi-generations or life span was assessed using genetically modified (GM) insect-resistant Bt11 corn. Diet containing 68% of GM Bt11 or non-Bt isoline with sufficient nutrient composition was fed to male and female ICR mice through 5 generations. The results of growth, mating, gestation, milking periods, reproduction and life span were not different between the GM Bt11 and non-Bt fed groups. The percentage of embryonic death, litter size, newborn sex ratio and body weight (21-60 days after birth) were not different between these groups. The life span of the third-generation mice did not differ over 1,072 days of observation. In addition, there was a tendency for a weight decrease among each group as the generations progressed, but there was no significant difference in performance among each group in each generation of mice.

Keywords

genetically modified; corn; biosafety; longterm performance; feeding study

Funding

Funding source
  • Not reported
Funding country
  • Not reported
Funding type
  • Not reported

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Cite this study

MLA

Haryu, Y, Y Taguchi, E Itakura, O Mikami, K Miura, T Saeki, Y Nakajima. "Longterm Biosafety Assessment of A Genetically Modified (GM) Plant: The Genetically Modified (GM) Insect-Resistant Bt11 Corn Does Not Affect the Performance of Multi-Generations or Life Span of Mice." The Open Plant Science Journal 3. (2009): 49-53. Web. 25 Jul. 2017.

APA

Haryu, Y., Taguchi, Y., Itakura, E., Mikami, O., Miura, K., Saeki, T., & Nakajima, Y. (2009). Longterm Biosafety Assessment of A Genetically Modified (GM) Plant: The Genetically Modified (GM) Insect-Resistant Bt11 Corn Does Not Affect the Performance of Multi-Generations or Life Span of Mice. The Open Plant Science Journal , 3( ), 49-53. doi:10.2174/1874294700903010049

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