There are currently 402 studies in the GENERA database.

Advanced Search

General Information

Document type
  • Peer-reviewed journal article
GE organism
  • soybean
GE trait
  • herbicide tolerance
Country
  • Brazil

Results

Equivalence
  • no effect
Safety for consumption
  • no effect

The impact of dietary organic and transgenic soy on the reproductive system of female adult rat Open Access

Brasil, FB; Soares, LL; Faria, TS; Boaventura, GT; Sampaio, FJ; Ramos, CF
The Anatomical Record. 2009 April. 292(4):587–594

Link to full text (open access, freely available)

PMID: 19301281 DOI: 10.1002/ar.20878

Abstract

The goal of this article was to compare the effects of a prolonged use of organic and transgenic soy on the lipid profile and ovary and uterus morphology. Wistar rats were fed three different diets from weaning until sacrifice at 15 months of age. The three diets were: casein-based diet control group (CG), organic soy-based diet group (OSG), or transgenic soy-based diet group (GMSG). There were no differences in food consumption or in the diet isoflavone components among the groups. Compared with the CG diet, both the OSG and GMSG diets were associated with significant reductions in body weight, serum triglycerides, and cholesterol (P < 0.05) (CG = 406 +/- 23.1; 104.3 +/- 13.2; 119.9 +/- 7.3 GMSG = 368 +/- 17.6; 60.3 +/- 4.6; 83.3 +/- 5.7 OSG = 389 +/- 23.5; 72.3 +/- 12.5; 95.5 +/- 8.0, respectively). The volume density of endometrial glandular epithelium was greater in the GMSG group (29.5 +/- 7.17, P < 0.001) when compared with the CG (18.5 +/- 7.4) and OSG (20.3 +/- 10.6) groups. The length density of endometrial glandular epithelium was shorter in both GMSG (567.6 +/- 41.1) and OSG (514.8 +/- 144.5) diets compared with the CG (P < 0.05) diet. GMSG also resulted in reduced follicle number and increased corpus luteum number compared to the OSG or CG diets (P < 0.05). In summary, both GMSG and OSG diets resulted in decreased body weight and lower serum triglyceride and cholesterol levels, and alterations in uterine and ovarian morphology were also observed. The prolonged use of soy-based diets and their relation to reproductive health warrants further investigation.

Keywords

transgenic soy; endometrium; ovary; estradiol; cholesterol

Funding

Funding source
  • Not reported
Funding country
  • Not reported
Funding type
  • Not reported

Links to outside analysis of this resource

Please contact us if you know of an independent summary or analysis of this resource.

Cite this study

MLA

Brasil, FB, LL Soares, TS Faria, GT Boaventura, FJ Sampaio, CF Ramos. "The impact of dietary organic and transgenic soy on the reproductive system of female adult rat." The Anatomical Record 292.4 (2009): 587–594. Web. 27 Jul. 2017.

APA

Brasil, FB., Soares, LL., Faria, TS., Boaventura, GT., Sampaio, FJ., & Ramos, CF. (2009). The impact of dietary organic and transgenic soy on the reproductive system of female adult rat. The Anatomical Record, 292(4), 587–594. doi:10.1002/ar.20878

Please verify citations before use, citations are automatically generated based on information stored within the GENERA database and therefore may or may not be correct.